Tefestrol - is a mixture of the sesquiterpene complex esters ferutinine (90%) and tenuferidine (10%), isolated from the plant ferula tenuisecta.Tefestrol exhibits estrogen-like action; the activity is the similar to synthetic estrogens. Administration of tefestrol induces enhancement proliferation of vaginal and endometrial mucus layers; stimulates feebly marked secondary female sex signs. Drug improves common disturbances caused by deficiency of sex glands activity. The preparation activates synthesis and secretion of luteinizing and folliculostimulating hormones of hypophysis and stimulates ovulation process.Tefestrol is prescribed for the treatment of pregnant women, in gynecology for the treatment of infertility and at the climacterium period. It is used for eradication of retardation of sexual maturation, disturbances of menstrual cycle, dysfunctional menorrhagias, feminal climax, interruption of pregnancy, infertility of endocrine genesis; for preparation and pathologic tendency of labor. Low toxicity of drug and soft therapeutic effect result in its long-term usage, available with hestagens, as a substitute therapy for many gynecologic diseases.In comparison with known drugs exerting the same effect such as sinestrol (hexestrol), diethylstilbestrol and ethenylestradiol. Tefestrol is natural compound from medicinal plant. It does not influence arterial pressure, it practically does not cause changes in the system of a hemostasis, does not change secretion endogenic estrogens. Its therapeutic dozes has no embryotoxicity. Due to its none-toxicity the preparation guarantees safe application in children`s gynecology.Available as substance and tablets, containing 0,005g of tefestrol.By protocol no7 (april 11,1986) of the pharmacological committee of ministry of health of the ussr the tefestrol has been approved to practical use. Clinical trials of the drug have been carried out among the 409 patients of the research centre on health protection of mother and child (moscow, ussr) and among about 3000 patients in clinics of uzbekistan.
Desoxypeganine hydrochioride is chloride salt of the alkaloid desoxypeganine from the Peganum harmala plant.Desoxypeganine hydrochioride is an inhibitor of cholinesterase. Its anticholinesterase effec
ACLESIN is a mixture of alkaloids, derived from roots of the Aconitum leucostomum plant.As antiarythmic drug, ACLESIN improves auricular and ventricular disturbances of heart rhythm, caused by differe
Cytisine - respiratory analeptic.Composition cytisine is quinolizidine alkaloid present in the seeds of thermopsis lancefljata.Cytisine is related to compounds of "ganglionic activity". The
Galanthamine hbr - inhibitor of cholinesterase. Galanthamine hydrobromide is bromhydrate salt of the alkaloid galantaminum, isolated from the galantus voronovi, galantus nivalis) and ungernia victori.
Helminthicide of wide spectrum action. They are effective against intestinal hemathelminthes.Medamine is used for the treatment of ascariasis, trichocephaliasis, enterobiasis, strongyloidiasis, ankylo
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