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Producer information
Company:
Hubei Yuancheng Gongchuang Tech Co.,LTD
 
Address:
No.496 Zhongshan Road Wuchang Area
 
Phone:
+86-027-50756039

Anamorelin


Anamorelin(RC1291; ONO-7643) is a synthetic orally active ghrelin receptor agonist which is under development for the management of non-small lung cancer associated cachexia/anorexia.Cas:249921-19-5MW:546.7MF:C31H42N6O3The solvent/solubility: 10 mM in DMSOIC50 Value:Target: GHSRAnamorelin hydrochloride is the orally bioavailable hydrochloride salt of a synthetic, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Stimulation of GHSR may also reduce the production of the pro-inflammatory cytokines TNF-alpha and interleukin-6, which may play a direct role in cancer-related loss of appetite.

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