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CAS 595-33-5 Megestrol Acetate
Product name:Megestrol AcetateCAS NO.: 595-33-5EINECS: 209-864-5Assay: 99%Molecular Formula:C24H32O4Molecular Weight:384.51Appearance: White or light yellow crystalline powder (methanol), odorless and tasteless. Melting point 214-216. Soluble in acetone, slightly soluble in ethanol, ethyl ether, insoluble in waterProduct DescriptionMegestrol acetate (INN, USAN, BAN, JAN) (abbreviated as MGA or MA, and sold mainly under the brand names Megace and Megace ES), also known as 17α-acetoxy-6-dehydro-6-methylprogesterone, is a steroidal progestin and progesterone derivative (specifically, a 17-hydroxylated progesterone) with predominantly progestational and antigonadotropic effects. Though sometimes referred to simply as megestrol, it is important to clarify that megestrol acetate is not the same as megestrol, which is a closely related but different compound.Megestrol acetate has powerful antiandrogenic and antiestrogenic effects in humans at sufficient doses, capable of decreasing circulating androgen and estrogen concentrations to castrate levels in both sexes and significantly lowering the expression of the androgen receptor (AR) and the estrogen receptor (ER) in the body; as an example, one study in men with benign prostatic hyperplasia who were treated with 120-160 mg of megestrol acetate per day for 3 to 11 days found average decreases in AR quantity of 73% and 86% in the cytoplasm and nucleus of prostatic cells, respectively.[12] These actions are likely the result of a strong activation of the PR, which suppresses the secretion of the gonadotropins-peptide hormones responsible for signaling the body to produce not only progesterone but also the androgens and the estrogens-from the pituitary gland as a form of negative feedback inhibition, and hence downregulates the hypothalamic-pituitary-gonadal (HPG) axis, resulting in decreased levels of the sex hormones and their associated enzymes, carriers (e.g., sex hormone-binding globulin), and receptors.It is the antiandrogenic and antiestrogenic effects of megestrol acetate mediated by suppression of the HPG axis that are believed to be largely responsible for its beneficial effects against androgen and estrogen-sensitive cancers, respectively.Usage:1. Mainly used for short-acting oral contraceptives, also can be used for intramuscular injection of long-acting contraceptives.2. For the treatment of dysmenorrhea, amenorrhea, dysfunctional uterine bleeding, endometriosis and endometrial adenocarcinomaIf you have any questions,welcome to ask me and send email to me.Payment Methods:West Union,Moeny Gram,PayPal and Bank TransferDelivery Ways:EMS,HKEMS,TNT,DHL,FedEX,UPS etcShipment Time:Within 8 hours after confirmation of your paymentOther Service:Safe shipment,high purity and best price for youOur mission:Provide our customer with an excellent personal service which develops long-term relationship, meeting their specific needs within budget and time frame. Ensure regulatory compliance are maximize on clients core competencies and product quality through optimized validated and controlled processes. Our vision:Promote initiative discipline, flexibility and team work through our consultants.Ensure that all of our services comply with customer requirements, policies, and procedures with local, federal and international agencies regulations.Product list: 1 Testosterone enanthate CAS: 315-37-72 Testosterone acetate CAS: 1045-69-83 Testosterone propionate CAS: 57-85-25 Testosterone cypionate CAS: 58-20-86 Testosterone phenylpropionate CAS: 1255-49-87 Testosterone isocaproate CAS: 15262-86-98 Testosterone decanoate CAS: 5721-91-59 Testosterone Sustanon 250 --10 Testosterone undecanoate CAS: 5949-44-011 Turinabol (4-Chlorotestosterone acetate) CAS: 855-19-612 Oral turinabol CAS: 2446-23-313 Stanolone (androstanolone) CAS: 521-18-614 Nandrolone Decanoate (DECA) CAS: 360-70-315 Nandrolone Cypionate CAS: 601-63-816 Nandrolone Phenypropionate (Durabolin) CAS: 62-90-817 Boldenone Undecylenate (Equipoise) CAS: 13103-34-918 Boldenone Acetate CAS :2363-59-919 Drostanolone Propionate (Masteron) CAS: 521-12-020 Drostanolone Enanthate CAS: 472-61-121 Superdrol Powder (methyl-drostanolone) CAS: 3381-88-222 Trenbolone Acetate (Finaplix H/Revalor-H) CAS: 10161-34-923 Trenbolone Enanthate (parabolan) CAS: 10161-33-824 Trenbolone Hexahydrobenzyl Carbonate CAS: 23454-33-325 Epiandrosterone CAS: 481-29-826 Dehydroisoandrosterone Acetate CAS: 853-23-627 7-keto DHEA (7-oxo DHEA) CAS: 566-19-828 Methenolone Enanthate (Primobolan) CAS: 303-42-429 Methenolone Acetate CAS: 434-05-930 Methandrostenolone(Dianabol) CAS: 72-63-931 Tamoxifen Citrate (Nolvadex) CAS: 54965-24-132 Clomiphene citrate CAS: 50-41-933 Toremifene citrate CAS: 89778-27-834 Letrazole(Femara) CAS: 112809-51-535 vardenafil CAS: 831217-01-736 Dapoxetine CAS: 119356-77-337 Dapoxetine HCl CAS: 1071929-03-738 Dutasteride CAS: 164656-23-939 Finasteride CAS: 98319-26-740 Yohimbine HCl CAS: 65-19-0 Peptides SpecificationMGF 2mgPEG MGF 2mgCJC-1295 with DAC 2mgCJC-1295 without DAC 2mgPT-141 10mgMT-1 10mgMT-2 10mgGHRP-2 5mgGHRP-2 10mgGHRP-6 5mgGHRP-6 10mgIpamorelin 2mgHexarelin 2mgSermorelin 2mgOxytocin 2mgTB500 2mgPentadecapeptide BPC 157 2mgTriptorelin 2mgTesamorelin 2mgGonadorelin 2mgGonadorelin 10mgDSIP 2mgSelank 5mg
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