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Theophylline
1. Quick Detail:Product Name: TheophyllineSynonyms: Theophylline anhydrous; 1,3-dimethyl-3,4,5,7-tetrahydro-1H-purine-2,6-dioneCAS: 58-55-9EINECS: 200-385-7MF: C7H10N4O2MW: 182.1799Assay: 99%Appearance: White powderDensity 1.62g/cm3Melting point 270-274℃Boiling point 390.1°C at 760 mmHgRefractive index 1.737Flash point 189.7°CWater solubility 8.3 g/L (20℃)Vapour Pressur 2.72E-06mmHg at 25°C 2. Descriptions:Theophylline, also known as 1,3-dimethylxanthine, is a methylxanthine drug used in therapy for respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma under a variety of brand names. As a member of the xanthine family, it bears structural and pharmacological similarity to theobromine and caffeine.The main actions of theophylline involve:relaxing bronchial smooth muscleincreasing heart muscle contractility and efficiency; as a positive inotropicincreasing heart rate: (positive chronotropic)increasing blood pressureincreasing renal blood flowanti-inflammatory effectscentral nervous system stimulatory effect mainly on the medullary respiratory center.The main therapeutic uses of theophylline are aimed at:chronic obstructive pulmonary disease (COPD)asthmainfant apneaBlocks the action of adenosine, an inhibitor neurotransmitter that induces sleep, contracts the smooth muscles and relaxes the cardiac muscle.
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