PEG-MGF
email:jaymee at ycphar dot com.
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MGF：2mg/vial
Sequence: Tyr - Gln - Pro - Pro - Ser - Thr - Asn - Lys - Asn - Thr - Lys - Ser - Gln - D - Arg - D - Arg - Lys - Gly - Ser - Thr - Phe - Glu - Glu - His - Lys - NH2
M.W: 2848.13
Solubility: Insoluble in water. Dissolve peptide in 50-100 µl of 60% Acetonitrile in water or DMSO, then dilute with any desired buffer.
Storage Condition: Store peptide in DRY form at 0-5°C.
Appearance: White powder
Content: The contents of this vial have been accurately determined to contain 100µg of NET peptide.
HPLC Analysis Purity ≥95%
PEG MGF, 2mg/vial
Function: Promotion Development Dosage
Form: Powder
PEG-MGF Sequence: PEG-Suc-Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Thr-Lys-Ser-Gln-D-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-His-Lys-NH2
Active Substance: It is PEGylated MGF
Application: PEGylation is the act of attaching a Polyethylene glycol (PEG) structure to another larger molecule (in this case, MGF). The PEG acts as a protective coating and the theory here is that this will allow the MGF to be carried through the blood stream without being broken down.
MGF, 2mg/vial Usage:
Mechano Factor (MGF) exhibits local effects in skeletal muscle and without cannot travel through the body without modification. The problem with synthetic Mechano Factor (MGF) is that it is introduced intramuscularly and is water based so it goes into the blood stream. When used this way, Mechano Factor (MGF) only remains stable in the blood stream for a few minutes. Biologically produced MGF is made locally and does not enter the bloodstream. It is also short acting so stability is not an issue. By PEGylating the Mechano Factor (MGF) it is almost as efficient as local produced Mechano Factor (MGF) when used intramuscularly. This is accomplished by surrounding part of the peptide with a structure of polyethylene glycol, which can be attached to a protein molecule. The polyethylene glycol groups protect the peptide but do not surround it completely. The active sites of the peptide are still free to do their biological function. In this case the shell is a negative charged shield against positively charged compounds that would affect the protein.
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