Epinephrine hydrogen tartrate (Steroids) Alias; Adrenalin tartrate;Adrenalinium;epinephrinetartrate;Suprarenin tartrate;CAS NO.:51-42-3 Molecular Formula:C9H13NO3.C4H6N6MW:333.29MS: Appearance: White or almost white crystals Assay: 98.0% min Packing: 20g-1kg /vacuum aluminum foil bag Description. A white to greyish white, crystalline powder; odourless.Solubility. Soluble in 3 parts of water; slightly soluble in ethanol (~750 g/l) TS; practically insoluble in ether R.Category. Sympathomimetic.Storage. Epinephrine hydrogen tartrate should be kept in a tightly closed container, protected from light.RequirementsDefinition. Epinephrine hydrogen tartrate contains not less than 98.0% and not more than 101.0% of C9H13NO3,C4H6O6, calculated with reference to the dried substance.Identity testsA. The absorption spectrum of a 0.10 mg/mL solution in hydrochloric acid (0.01 mol/l) VS, when observed between 230 nm and 350 nm exhibits a maximum at about 280 nm; the absorbance of a 1-cm layer at this wavelength is about 0.8.B. Dissolve 10 mg in 10 mL of water and transfer 1 mL to a flask containing 10 mL of buffer phthalate, pH 3.4, TS; another buffer having the same pH may also be used. Add 0.5 mL of iodine (0.1 mol/l) VS, and allow to stand for 5 minutes. Add 2 mL of sodium thiosulfate (0.1 mol/l) VS, and allow to stand for 1 minute; a strong red colour is produced (distinction from levarterenol, which gives a clear solution with a pink tinge).C. The filtrate obtained when carrying out the determination of specific optical rotation (see below) yields reaction B described under 2.1 General identification tests, as characteristic of tartrates.cindy1114 (at)ycccreate (dot)com
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Так же в категории "Прочие фармацевтические препараты":