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Quick Details:
Eplerenone
Chemical Name: Pregn-4-ene-7,21-dicarboxylic acid 9,11-epoxy-17-hydroxy-3-oxo gamma-
lactone methyl ester
CAS NO.: 107724-20-9
Molecular Formula: C24H30O6
Assy:99%
Purity: 99%
Molecular weight: 414.49
Density: 1.31 g/cm3
Melting Point: 241-243 °C
Boiling Point: 597.933 °C at 760 mmHg
Flash Point: 259.474 °C
Storage: Keep it under seal in cool and dark place
Appearance: white crystalline powder; slightly soluble in water.
Standard: Enterprise Standard
Uses:EPL is a selective aldosterone receptor antagonist, it only applied to the mineralocorticoid receptor, and not the male hormone and progesterone receptor. EPL treatment for 1 and 2 of the patients with hypertension, efficiency and reduce systolic blood pressure and diastolic blood pressure amplitude and enalapril similar. Angiotensin converting enzyme inhibitors and angiotensin II receptor inhibitor effect of poor low renin levels in patients with essential hypertension, EPL also has good antihypertensive effect. Also has better antihypertensive effect on isolated systolic hypertension, has good antihypertensive effect on diet induced obesity related hypertension. In addition, ultrafiltration EPL can significantly reduce glomerular hypertension, can reduce albuminuria, for patients with hypertension and diabetes, renal protective effect of the more obvious.
Eplerenone is used for:
Treating high blood pressure alone or along with other medicines. It is also used to improve survival in patients who have certain heart problems (left ventricular systolic dysfunction and congestive heart failure) following a heart attack. It may also be used for other conditions as determined by your doctor.
Eplerenone is an aldosterone blocker. It works by blocking the hormone aldosterone, which lowers the amount of sodium and water the body retains. This helps to lower blood pressure to help prevent strokes, heart attacks, and kidney problems.
How to use eplerenone:
Use eplerenone as directed by your doctor. Check the label on the medicine for exact dosing instructions.
•Take eplerenone by mouth with or without food.
•Take eplerenone regularly to receive the most benefit from it. Taking eplerenone at the same time each day will help you remember to take it.
•If you miss a dose of eplerenone, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Superiority
Estrogen is a female sex hormone, produced by the ovaries and placenta. Adrenal cortex also produced a few estrogen. Female children after puberty ovarian secretion of estrogen, start, in order to promote the vagina, uterus, fallopian tube and ovary itself development, at the same time caused menstrual endometrial hyperplasia. Estrogen can promote the subcutaneous fat accumulation, plump; hyperplasia of the breast, nipple, areola dark colors, and produce sexual desire; to promote the body sodium and water retention, bone calcium deposition
EstradiolSynonyms: BETA-ESTRADIOL-16,16,17-D3CAS: 50-28-2 MF: C18H24O2MW: 272.38 Content: 99%Properties: white crystalline powderProduct description: Estradiol is a sex hormone that is present in both
EstradiolProduct name: EstradiolCAS No.: 50-28-2M.F.: C18H24O2M.W.: 272.38Assays: 98.66%Packing: 5kg/tinReference Standard: USP28Appearance: White or creamy white crystalline powder
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