AICAR AcadesineI am Lisa, email: lisa at ycgmp dot com, Skype:poisedtoni, Tel: +86-18872220727, you can add me on Whatsapp if you are using that. Contact Lisa, you would never regret.CAS: 2627-69-2MF: C9H14N4O5MW: 258.23EINECS: 220-097-5mp 214-215 °Cstorage temp. −20°Csolubility H2O: >10 mg/mLform powdercolor tanAICAR Usage And Synthesisadenosine regulating agents Acadesine is the prototype of a new class of compounds termed adenosine regulating agents. Acadesine is a purine nucleosid analogue that enters the myocyte and is immediately phosphorylated to ZMP (AICA ribotide), which is further metabolised to Inosine mono-phosphate (an intermediate in the synthesis ofadenosine triphosphate (ATP) and guanosine triphos-phate). Claims that acadesine may serve as a substrate for ATP synthesis and result in repletion of myocardial ATP were supported by some studies and refuted by others. Because acadesine may be a precursor in the synthesis of myocardial ATP it was proposed as a possible agent of myocardial protection during ischaemia, particularly because myocardial ATP depletion has been linked to cell death.Chemical Properties SolidUsage glucose uptake stimulant; AMPK activatorUsage AICAR is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) hav e been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.Biological Activity Cell-permeable, allosteric activator of AMP-activated protein kinase (AMPK). Augments proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells and attenuates psychosine-induced expression of proinflammatory cytokines and iNOS in astrocytes.AICAR Preparation Products And Raw materialsProduct Categories: Bases & Related Reagents;Carbohydrates & Derivatives;Nucleotides;Protein Kinase;ARASINE;Cardiovascular APIs;PI3K/Akt/mTORSynonyms: ACADESINE;AICAR;AICA-RIBOSIDE;AMPK;5-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-RIBOSIDE;5-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-B-D-RIBOFURANOSIDE;5-AMINOIMIDAZOLE-4-CARBOXAMIDE 1-BETA-D-RIBOFURANOSIDE;Z-RIBOSIDE
Anti Estrogen Steroids Powder Anastrozole for Women Breast CancerSynonyms:ArimidexCAS No. 120511-73-1 Formula C17H19N5 Molecular Weight 293.37 Density 1.085 gcm3 Melting Point 81 - 82 ° C Boiling
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