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SpironolactoneProdcut name: SpironolactoneSynonym: Aldactone;Antisterone;spirolactone;7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta- carbolactoneCAS Registry Number: 52-01-7Assay: 99%Packaging: 1kg/foil bagMolecular Formula: C24H32O4SMolecular Weight: 416.5735Appearance: White or almost white fine crystalline powder;Slightly bitter taste, odourless or slightly mercaptan odor.Insoluble in water, soluble in ethanol, soluble in benzene or ethyl acetate.Description:It is a synthetic, steroidal antimineralocorticoid and antiandrogen that also has some weak progestogen properties, as well as some indirect estrogen and glucocorticoid effects. It is used primarily as a diuretic and antihypertensive, but may also be employed for the purpose of reducing elevated or unwanted androgen activity in the body.It acts predominantly as an antagonist of the mineralocorticoid (or aldosterone) and androgen receptors, and in relation to its antimineralocorticoid effects, belongs to a class of pharmaceutical drugs known as potassium-sparing diuretics.Applications:Spironolactone is competitive inhibition of aldosterone drugs, drug itself is not active, role is diuresis and endogenous competitive aldosterone antagonist and happen, belongs to the potassium diuretics.
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