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Keywords
5-apb
286834-80-8
5apb
Quick Details
ProName: 5-apb,cas no.286834-80-8
CasNo: 286834-80-8
Appearance: white crystalline powder
Application: For lab research
DeliveryTime: 2 days
PackAge: aluminium foil bag
Port: Tianjin and Shanghai
ProductionCapacity: 100 Kilogram/Week
Purity: 99%
Storage: keep in airy and dry place
Transportation: EMS,DHL,USPS,FedEx
LimitNum: 5 Gram
Grade: Pharma Grade,Other
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Details
CAS No.: 286834-80-8
Formula: C11H13NO
Mol.Mass 175.23 g/mol
5-(2-aminopropyl)benzofuran or 1-benzofuran-5-ylpropan-2-amine (5-APB) is a triple monoamine reuptake inhibitor with Ki values of 180, 265 and 811 for NET, DAT and SERT respectively as well as being a potent agonistfor the 5-HT2B receptor (Ki 14nM).This agonism for 5-HT2B makes it likely that 5-APB would be cardiotoxic with long term use, as seen in other 5-HT2B agonists such as fenfluramine and MDMA. The subjective effects andstructure-activity relationship suggest that 5-APB is also a monoamine releasing agent.
5-APB is commonly found as the succinate and hydrochloride salt. The hydrochloride salt is 10% more potent by mass and doses should be adjusted accordingly.
5-APB is also an agonist of the 5-HT2C receptor as well as a triple monoamine reuptake inhibitor.It has been sold as a designer drug since 2010. Anecdotal reports from users suggest it has stimulant and empathogeniceffects, but less psychedelic action than related compounds such as 6-APB and 5-APDB.
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